High Blood Pressure Research Council of Australia

 

HBPRCA Email Newsletter

June 2009

 

 

Welcome Note from Geoff Head

Welcome to the midyear e-news coming straight after the very successful European Hypertension meeting in Milan that many of our members attended. Some of the highlights at that meeting included the studies by our own Markus Schlaich and Murray Esler who presented the impressive results on the effectiveness of selective renal denervation in resistant hypertensive subjects.  A number of our members including our president Stephen Harrap were part of two oral presentations of the ADVANCE study featured in the clinical trials section. The HBPRCA initiated and supported study on the comparison of ambulatory and clinic blood pressure opened the meeting on the Saturday (see ABPM working group report).

 

Our feature article this month comes from Alta Schutte who is an Associate Professor and Coordinator of the Hypertension in Africa Research Team (HART) at the North-West University, Potchefstroom in the north west province of South Africa which was the first town and capitol of the formerly Transvaal republic. Alta is intending to attend our Sydney ASM hopefully strengthening our common interests and links beyond cricket. We hope that everyone will make her feel welcome.

 

ISH2012 – As you are all aware, the HBPRCA will be hosting ISH2012 in Sydney, 30 September – 3 October. As members of the HBPRCA, we would like you to advertise the Congress, by downloading the slides and including them at the end of your presentations. Please click here to download.

 

ISH2010 – will be in Vancouver on the 26th-30th September. PowerPoint slides for this meeting are available here.

 

President’s Message

2009 Annual Scientific Meeting News

2009 Workshop News

Student News

Membership News

Society Liaison News

IMPORTANT INFORMATION: Clinical and Experimental Pharmacology and Physiology (CEPP) Subscription

Feature article: The Challenges of Hypertension Research in South Africa, by Aletta Schutte

Ambulatory Blood Pressure Monitoring (ABPM) Working Group Initiative

Petition: Support for Humane Animal Research

Foundation for High Blood Pressure Research

Upcoming Meetings

 

 

President’s Message from Stephen Harrap

This message comes to you from Paris, where I am working with Xavier Jeunemaître and his team at the Research Centre in the Georges Pompidou Hospital (shown in the photo along with the marvellous Velib’ bikes that can be hired for $2 per day). My visit is supported by the Franco-Australian Exchange Program, which is now entering its second year and has attracted some terrific applicants this time, which augers well for ongoing success of this program with the Société Française d'Hypertension Artérielle. Congratulations to Erin O’Callaghan and see the report from Bruce Neal below for news of this program.


There has been much preparation for the forthcoming Annual Scientific Meeting in Sydney and we look forward to receiving all your abstracts to make this another successful meeting. There has been a terrific effort by Geoff Head with Kate Denton and Markus Schlaich with a great committee putting together the plans for the Workshop, of which you can read more below.

 
The Council, with cognate organisations, continues to look at ways in which it can raise the awareness of blood pressure with government. We have been investigating the possibility of commissioning a report by Access Economics and achieving some liaison with Rob Moodie’s Health Taskforce on Prevention.  We are hoping to devise a cost effective means of achieving this goal and we might have to fall back on the expertise of the Council to help formulate a document that make government sit up and listen.


The Council continues to have a presence in General Practices throughout Australia, with the distribution of the second in the DVD series “Off The Cuff” with special presentations by Michael O’Rourke and Stephen Hunyor. We have also been able to place our own Blood Pressure Awareness posters in general practices through a generous free arrangement with Medical Media. The messages were simple:

 

1.       Do you measure blood pressure in every patient at least once a year?

2.       Do you measure blood pressure in hypertensive patients every time you see them?

3.       Do you always believe the blood pressure reading?

4.       Do you change management on the basis of those readings?

 

We shall have an opportunity for another round of Blood Pressure messages in December.


We have also been pleased by the number of research teams that have been able to take advantage of the Omron semi-automated blood pressure machines that we have set aside for temporary use in appropriate projects.


As always, there is much happening and you’ll enjoy reading this eNews, I’m sure.

 

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2009 Annual Scientific Meeting News from Kate Denton and Markus Schlaich

IMPORTANT: Don’t forget that the meeting is being held from Tuesday 1st to Thursday 3rd December this year.

 

Half way through the year all ready! However, plans for the HBPRC meeting 2009 are well advanced.  The invited speakers are organised and include RD Wright Lecturer, Prof Frans Leenan – Central mechanisms in determining sympathetic hyperactivity in salt-sensitive hypertension and congestive heart failure.  Austin Doyle, Prof Michael Cowley – How and why the brain becomes resistant to signals that are meant to convey that the body has sufficient stores of energy, and should start to burn more, and eat less.  Colin Johnston, Dr Alex Brown – Indigenous cardiovascular disease disparity and its determinants.  The meeting is being held at Crystal Palace near Luna Park in Sydney and I am looking forward to taking a ferry trip and the Sky Safari cable car ride to the Conference Dinner, which will be held at Sydney’s famous Taronga Zoo on Wednesday 2nd December.

 

Registration and abstract submissions are now officially open on-line and via paper form. For information on the meeting, please visit the website.

 

Please put this in your diaries now!

1 – 3 December 2009
Luna Park Sydney

 

Close of abstracts

Friday 4 September 2009

Close of EB registrations

Friday 23 October 2009

 

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Workshop News from Geoff Head

ASM Workshop Tuesday 1st December 2009: “Environmentally Influenced Cardiovascular Disease: From the Fetus to the Adult”

Obesity and its associated conditions, both metabolic and cardiovascular, are a major threat to human health. The increased incidence of obesity is observed worldwide, but is highest in westernised countries including Australia. The cardiovascular consequence of this trend is disturbing but quite predictable since there is a very strong relationship between body mass index and levels of blood pressure. Management and treatment of obesity related hypertension poses a formidable challenge with recent data suggesting that up to 70% of newly diagnosed hypertensive cases in the Framingham study are attributable to obesity. This phenomenon is affecting not only adults but there is increasing recognition that there is a relationship between hypertension and obesity that affects children. We are now realising that even the fetus is very much affected by its in utero environment such that factors influencing fetal development can program the offspring to develop obesity, hypertension and related cardiovascular disease. This increased incidence of overweight status in young children is alarming and suggests that this problem will only escalate in the future.

 

This workshop held over a single day will attempt to bring together various streams of research by scientists and clinicians involved in the environmental influences leading to cardiovascular disease. The plan is for sessions involving fetal programming, children's issues through to the adult with attention to special areas of concern such as indigenous Australians.

The program is taking shape very quickly with 23 confirmed speakers for the day including our invited international guest Kevin Grove from Oregon National Primate Research Center in Portland. Kevin's long-term interests lie in determining the role that maternal and early postnatal health and diet has on the development of metabolic systems and on the circuits in the brain that control these systems.

 

The format for the day will be 3 sessions finishing with a debate

Session 1             Early Life Programming of Cardiovascular disease

Session 2             Early Life Programming of Obesity

Session 3             Adult obesity and cardiovascular disease

Debate topic         Lap band Surgery is better than diet and exercise for controlling the obesity epidemic

 

Workshop Committee: Geoff Head, Kate Denton, Markus Schlaich, Louise Burrell, James Armitage, Mary Wlodek, Bruce Neal and Annemarie Hennessy

 

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Student News from Erin O’Callaghan

We would like to remind HBPRCA members to ensure students apply for (free) membership to the HBPRCA by the 30th of September.  Among many other benefits, students who are members by this date will be eligible for travel grants to this year’s ASM in Sydney.  Application forms are available on the HBPRCA website.

 

We have received valuable responses from current student members detailing their appreciation of the 2008 ASM, with particular praise for the inaugurated Student’s Choice Best Poster Award category.  The theme for the 2009 ASM student symposium will be focused on life after thesis submission and we are currently sourcing speakers to share their experiences on this topic.

 

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Membership News from Doug McKitrick

Thank you to those of you that have taken the time to renew your membership. Membership information for 2009 will be finalised shortly and the HBPRCA has continued to grow. It is a great time to be part of a vibrant, changing and growing scientific society.

 

The helpful reminders for those of you who haven’t renewed your subscription will soon cease. Your ability to renew will not cease and may still be done by mail, fax or internet. If you have internet access go to the HBPRCA website and follow the link for access to the secure payment site, or to download a form for return by fax or post. If you don’t have internet access, can’t remember if you have paid, or just need a bit of help, please contact the Secretariat (details below). Remember to encourage the participation of your graduate students, and provide them with the career-building opportunity to take advantage of free HBPRCA membership.

 

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Society Liaison News from Bruce Neal

British Hypertension Society

The British Hypertension Society has now finalized the agenda for its September meeting.  We will be well represented with a strong Australian contingent - Amanda Sampson (while an honorary Glaswegian at the moment!) will be giving an oral presentation, Anne Barden will be presenting a poster and Stephen Harrap will be starring as an Invited Speaker.  While the BHS meeting is usually restricted to its association members of the HBPRCA are now invited to participate as guests of the president.  You will have to cover your own travel but the subsidized registration fee will secure two nights of accommodation and two days of high quality science, entertainment, meals and drinks.  Please let us know if you plan to attend the meeting, which promises to be a great event. Please login to the HBPRCA to view the program.

 

Franco – Australian Exchange

The second award of the Franco-Australian Exchange travel grant was made this month to Erin O’Callaghan from the University of Melbourne.  Erin will be spending 3 months working with Genevieve Nguyen at the College de France Center for Interdisciplinary Research in Biology at INSERM.  Her work will seek to determine the distribution of the (pro) renin receptor in the cardiovascular centres of the rat brain.  Dr Nguyen has unique expertise in the detection and characterization of the (pro) renin receptor having conducted the seminal work in this field.  We wish Erin all the best for her travels.

 

We await word from the French Society about their successful candidate and who they will be visiting in Australia.  Once we do hear we will let you know.  We are keen that visiting researchers have the maximum possible exposure to Australian science please do get in touch if you would like to meet up with them during the time that they are in Australia.

 

American Heart Association Council for High Blood Pressure Research

Following the success of the French and British exchange schemes we are delighted that we have now crystallized a similar plan for interaction with our US colleagues.  Michael De Silva is the inaugural awardee of the Australian-American exchange program and will be presenting at the forth-coming 63rd meeting of the High Blood Pressure Research Council of the American Heart Association that will be held in Chicago in September of this year.  Michael will also be presenting seminars at two laboratory visits he will make during his trip and we look forward to hearing from him once he is back. To visit the website, please click here.

 

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Clinical and Experimental Pharmacology and Physiology (CEPP) Subscription

Servier has been a long-standing supporter of the Council providing support over many years for a number of our activities. While Servier will continue to support Council activities including their Corporate Membership, the publication of ASM abstracts in Hypertension and the Franco-Australian Exchange programs, it was with regret that they have informed us that they have decided that they can no longer support the subscription to Clinical and Experimental Pharmacology and Physiology for individual members of the Council.

 

Although it is disappointing that such circumstances have forced these financial decisions, the Council very much appreciates the long-term support by Servier for subscription to Clinical and Experimental Pharmacology and Physiology.

 

The Council will endeavour to continue its long-term scientific collaboration with CEPP and encourages all council members to consider either their own subscription or accessing the journal through institutional or other arrangements.

 

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Feature Article: The Challenges of Hypertension Research in South Africa from Aletta Schutte

Aletta Schutte, Research Scientists, Hypertension in Africa Research Team (HART), School for Physiology, Nutrition and Consumer Sciences, North-West University, Potchefstroom, South Africa

 

The hypertension “situation”

In South Africa, hypertension is a widespread problem of immense economic importance because of its high prevalence in urban areas, its frequent underdiagnosis, and the severity of its complications.1 As a result, black South Africans have a stroke mortality rate twice as high as that of Caucasians. Therefore at the core of our research group, the Hypertension in Africa Research Team (HART) is our main vision highlighting the alleviation of the immense burden of cardiovascular disease in South African communities.

 

Multiple causative factors have been proposed to explain the high hypertension prevalence, including lower plasma renin levels, 2 sodium abnormalities,3 epithelial sodium channel changes,2 altered genes regulating the renin-angiotensin-aldosterone system, 2 increased peripheral vascular resistance1 as well as increasing obesity prevalence.4

 

Various approaches are possible to tackle the immense problem of hypertension – e.g. on genetic or molecular level; clinically as well as epidemiologically. There are already established research groups in South Africa focusing on genetic origins of cardiovascular disease in Africans and the Medical Research Council actively provides information regarding population statistics of cardiovascular disease and stroke. But little clinical research is being done regarding the functional and structural vascular changes taking place with the development of hypertension. Our group realised that we will be able to significantly contribute to this field by specifically studying the influences of certain key areas such as known and novel biochemical factors, obesity, urbanisation, HIV infection, and psychological stress on vascular function. By combining biochemical markers with measurements such as pulse wave velocity, intima-media thickness, carotid distensibility, the augmentation index, ambulatory and continuous blood pressure and ECG measurements, as well as static and dynamic retinal vessel analysis, we hope to contribute significantly to the understanding, but also the prevention of atherosclerosis and cardiovascular disease in black South Africans.

 

We work inter and trans-disciplinary with other research entities at the North-West University, and are also grateful towards our international collaborators (including Prof. RH Boëger, Prof. PEH Schwarz, Prof. T Ziemssen, Dr. M Reimann, Germany; Prof. H Marcoyannopoulou-Fojas, Greece; Prof. S Yusuf, Prof. N Frasure-Smith, Canada, Dr. M Hamer, United Kingdom; Prof. F Lespérance, France, Dr. A Alkerwi, Luxembourg). We also engage in research discussions with world experts in the field of hypertension and vascular dysfunction, such as Prof. Luc van Bortel (Ghent). And we have collaborated with scientists from Australia with regards to research in Indigenous Australian populations. Currently we are discussing possible collaboration with Prof. Peter Howe at the University of South Australia.

 

Urbanisation and obesity

Besides the high hypertension prevalence in South African urban areas, rapid urbanisation has also led to high rates of obesity, especially amongst urban black African women.5, 6 The South African Demographic and Health Survey showed in 1998 that 56.6% of South African women were overweight or obese.5 Unfortunately, obesity is becoming even more revered amongst African women because it signals HIV negativity and wealth.7 Due to the known detrimental cardiovascular effects of obesity, we have performed the multidisciplinary POWIRS study (Profiles of Obese Women and the Insulin Resistance Syndrome). A total of 100 lean, overweight and obese urban African women were individually matched according to age and body mass index with Caucasian women8. We hypothesised that obesity is the driving force for the high levels of hypertension observed in urbanised black South Africans. However, our results have shown that although urban African women have significantly higher blood pressure than age and body-mass index-matched Caucasians, their obesity levels are weakly related to traditional cardiovascular risk factors compared to Caucasian women. Our results, however, suggest a link of obesity with the development of insulin resistance and the metabolic syndrome.9-11 Our group was also the first to study the different links between adipokines (leptin12, 13, adiponectin14, visfatin15 and resistin9), vascular risk markers (Von Willebrand factor16, plasminogen activator inhibitor-1 (PAI-1)17, fibrinogen18, asymmetric dimethyl arginine (ADMA)19), inflammatory markers (hsCRP, hsTNF-alpha18) and insulin resistance (HOMA20, C-peptide21) with cardiovascular risk markers in African and Caucasian women. Interestingly we have found in most instances that the levels or absolute values of these markers are similar between the two ethnic groups, but we found ethnic disparities regarding the functioning of these markers in relation to cardiovascular function.

 

One of the main drawbacks of this and other studies conducted by our group in the past is the cross-sectional nature, which meant we were unable to determine cause-effect relationships. In order to address this problem our group started to collaborate with Professor Salim Yusuf (Canada) who also led the InterHEART study. We collaborate with him in the international PURE study (Prospective Urban Rural Epidemiology), which involves more than 20 developing countries. In 2005 a total of 2000 African participants were included in this study, and a first follow-up was conducted in 2008. We plan to continue this longitudinal study for a total of 12 years to investigate the main contributors to the development of hypertension and cardiovascular mortalities in the African population. Apart from addressing the main research questions as posed by the main PURE coordinating team, we also included our focused research questions, and performed additional measurements in this population, such as arterial stiffness measurements (pulse wave velocity).

 

The number one “threat” in South Africa

Despite the well-known effects of hypertension on morbidity and mortality of black South Africans, it is not the main threat. Almost a third of all new human immunodeficiency virus (HIV) infections and acquired immunodeficiency syndrome (AIDS) related deaths worldwide is accounted for in southern Africa and an estimated 5.5 million people are living with HIV in South Africa.22

 

Several cardiovascular risk factors have been associated with, or observed in the HIV-infected population probably explained by the longer life expectancy due to highly active antiretroviral therapy (HAART). There is however, still uncertainty about the relative contribution of the infection, the virus itself, the associated inflammatory response, the antiretroviral therapy, and the interaction between them to these cardiovascular risk factors. Hsue et al.23 reasons that HIV infection itself should count as a coronary risk factor, within the list of traditional cardiovascular risk factors (smoking, hypertension, hypercholesterolemia, and diabetes). We are therefore now investigating the follow-up data within the PURE study, where a total of 15% of participants were HIV positive, to determine which parameters seem to be the main contributors to the vascular dysfunction observed in HIV positive individuals. What make our study unique are that since the start of the study four years ago, only half of the HIV positive subjects are using HAART therapy, and we are therefore able to study the effects of the HIV infection itself, as well as the therapy with regards to vascular deterioration when compared to a matched control group.

 

The importance of psychosocial factors

During 2008 and 2009 HART engaged in a new study, which included 400 African and Caucasian schoolteachers. The SABPA study (Sympathetic activity and Ambulatory Blood Pressure in Africans), which also received an award from the Metabolic Syndrome Institute in France, is the first study on Africans to evaluate the relationship between higher sympathetic activity, hypertension and poorer psychosocial wellbeing. In order to examine the hypothesized relationships, a multidisciplinary team of experts from the health, natural and social sciences are involved, consisting of researchers from Physiology, Nursing, Nutrition, Pharmacology, Biokinetics, Biochemistry, Psychology and Education as well as international expert teams from Canada and Britain (psychophysiologists), Luxemburg (epidemiologist), Netherlands and Sweden (sonographists), as well as Germany (autonomic dysfunction). We have found in our previous epidemiological work that an active or passive coping pattern as well as rural or urban status could have a significant influence on blood pressure.24, 25 An important part of this study is thus to involve psychophysiological stress testing, involving measurement of physiological responses to laboratory-induced stress as well as an array of other cardiovascular measures (ambulatory blood pressure, IMT, pulse wave velocity, biochemical markers, etc) to shed more light on the important relationship between psychophysiological stress and hypertension.

To conclude ...

It is extremely challenging to study hypertension in South African population groups where a vast range of causal factors for this condition needs to be taken into account. I am nevertheless pleased and honoured to be one of a handful of South African researchers tackling this problem hands-on – hoping to provide better conditions for many (who are in most instances not even aware of their hypertensive condition yet). Our research group, HART, invite interested Australian researchers to collaborate with us with regards to our existing data or future projects. As shown above, we have various interests and hope to take hands in order to lighten the heavy weight of cardiovascular disease.

 

 

References

                (1)           Opie LH, Seedat YK. Circulation 2005 December 6;112(23):3562-8.

                (2)           Hoosen S, Seedat YK, Bhigjee AI, Neerahoo RM. J Hypertens 1985 August;3(4):351-8.

                (3)           Worthington MG, Wendt MC, Opie LH. J Hum Hypertens 1993 June;7(3):291-7.

                (4)           Joubert J, Norman R, Bradshaw D, et al. S Afr Med J 2007 August;97(8 Pt 2):683-90.

                (5)           Puoane T, Steyn K, Bradshaw D, et al. Obes Res 2002 October;10(10):1038-48.

                (6)           Walker AR, Adam F, Walker BF. Public Health 2001 November;115(6):368-72.

                (7)           Bateman C. S Afr Med J 2007 July;97(7):490.

                (8)           Schutte AE, Kruger HS, Wissing MP, et al. S Afr J Sci 2005;101:61-7.

                (9)           Schutte AE, Huisman HW, van Rooyen JM, et al. J Hum Hypertens 2008; 22:528-536.

                (10)         Schutte AE, Olckers A. Horm Metab Res 2007 September;39(9):651-657.

                (11)         Schutte AE, Schutte R, Huisman HW, et al. Horm Metab Res 2009 February;41(2):79-85.

                (12)         Schutte R, Huisman HW, Schutte AE, et al. J Hum Hypertens 2005 July;19(7):535-41.

                (13)         Schutte R, Huisman HW, Schutte AE, et al. J Hum Hypertens 2005 December;19(12):933-9.

                (14)         Schutte AE, Huisman HW, Schutte R, et al. Eur J Endocrinol 2007 August;157(2):181-8.

                (15)         Reimann M, Ziemssen T, Huisman HW, et al. Obesity (Silver Spring) 2009 May 14.

                (16)         Schutte R, Schutte AE, van Rooyen JM, et al. Am J Hypertens 2008 December;21(12):1298-303.

                (17)         Greyling A, Pieters M, Hoekstra T, et al. Nutr Metab Cardiovasc Dis 2006 August 7.

                (18)         Schutte AE, van Vuuren D, van Rooyen JM, et al. J Hum Hypertens 2006 November;20(11):850-9.

                (19)         Reimann M, Schutte AE, Malan NT, et al. Exp Clin Endocrinol Diabetes 2007 October;115(9):600-5.

                (20)         Reimann M, Schutte AE, Schwarz PE. Horm Metab Res 2007 December;39(12):853-7.

                (21)         Reimann M, Schutte AE, Huisman HW, et al. Diabetes Res Clin Pract 2007 July;77(1):62-9.

                (22)         UNAIDS. Sub-Saharan Africa. AIDS epidemic update. Regional Summary.  2008.

                (23)         Hsue PY, Giri K, Erickson S, et al. Circulation 2004 January 27;109(3):316-9.

                (24)         Malan L, Schutte AE, Malan NT, et al. Biol Psychol 2006 June;72(3):305-10.

                (25)         Malan L, Schutte AE, Malan NT, et al. Int J Psychophysiol 2006 August;61(2):158-66.

 

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Ambulatory Blood Pressure Monitoring (ABPM) Working Group Initiative

Members: Geoff Head, Susie Mihailidou, Karen Duggan, Alexandra Bune, James Sharman, Arduino Mangoni, Peter Howe, Narelle Berry, Diane Cowley, Michael Stowasser, Lawrie Beilin, Jonathan Hodgson, John Chalmers, Carla Morey, Mark Nelson, and Mark Brown

 

The aim of this working group was to develop a clinical research collaborative to provide sufficient data to derive a robust algorithm, which can link ambulatory blood pressure monitoring (ABPM) (24hr average or awake average) readings to clinic blood pressure (BP). So far we are pleased to have received contributions from 10 research centres from 6 states totally over 6000 subjects with clinica and ambulatory values.  The results from the study have been presented at the European Society of Hypertension meeting in Milan recently and are currently being prepared for publication. The main findings were that at each clinic DBP and SBP target, predicted levels of day ABPM were quite similar (within 1 mmHg). This contrasts with the PAMELA study, which showed much lower ABPM values compared to clinic readings, which were measured by doctors.

 

Recently, we have included 1632 Doctor measured clinic BP from 3 centres, which gave values much higher than the main data set. The predicted ABPM values closely matched the PAMELA study findings.

 

 

Lower Limit of Grade 1 Hypertension

 

 

Doctor Clinic

24Hr

Day

Night

PAMELA

SBP

140

123

128

112

Australian

SBP

140

126

129

113

Difference between studies

 

3

1

1

PAMELA

SBP

90

77

82

67

Australian

SBP

90

78

81

69

Difference between studies

 

1

-1

2

 

The progress has been greatly assisted by the funding from the Council for 2 months of a project officer to complete the analysis.

 

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American Petition: Support for Humane Animal Research

Gary Sieck, President of the American Physiological Society recently asked members of the American Physiological Society to add their voice to those of other scientists showing their support for humane animal research. Research advocates at Americans for Medical Progress, UCLA Pro-Test and Speaking of Research have set up an online petition supporting humane animal research. Please consider adding your name, as we have, by going to http://www.raisingvoices.net/.

 

The Pro-Test Petition was inspired by a 2006 petition in the U.K. that gathered the signatures of over 20,000 people, including then Prime Minister Tony Blair. That petition helped to turn the tide of public opinion in the U.K in favour of animal research. As a result, in 2008, supporters of research were able to celebrate the completion of a laboratory in Oxford whose construction had been halted for more than a year due to harassment and intimidation by animal rights extremists.

 

Gary said “With violence against researchers escalating in the U.S., now is the time for members of the research community to publicly reaffirm the need for humane animal research. The APS has long been proud of the role it has played in promoting humane animal research and will continue to support such research in the future. “

 

He also encouraged others to sign and while this call was for Americans to do so, it is important that members of the Council are aware of such issues internationally. You may decide to support our American colleagues in this issue or possibly to consider doing the same here in Australia. Food for thought.

 

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Foundation for High Blood Pressure Research

2010 – 2011 Postdoctoral Research Fellowship

The Foundation is offering a two-year postdoctoral fellowship for a research project in hypertension or related fields in basic, clinical or public health areas at an Australian institution. Applications from biomedical, clinical and public health researchers are invited.

 

Applications are open to Australian citizens or permanent residents.

 

It is expected that the successful applicant will have had not less than five and not more than ten years' postdoctoral experience. The fellowship provides a salary and modest project maintenance costs.

 

2010 ISH Visiting Postdoctoral Award

The ISH Visiting Postdoctoral Award has been designed to encourage experienced researchers from countries other than Australia to work in Australia for up to two years on a specific research project in hypertension or a related field in basic, clinical or public health areas.

 

The ISH Visiting Postdoctoral Award will be awarded to an Australian research institution, as a contribution towards the salary of a postdoctoral researcher who is not an Australian citizen or permanent resident.

 

Application Procedures

For information on how to apply please contact:

FHBPR Secretariat

Department of Physiology

University of Melbourne

Parkville 3010

Victoria. Australia

Email: jkelly@unimelb.edu.au

 

Applications close on Friday 28 August 2009

 

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Upcoming Meetings

The Science of Salt: Industry innovation and best practice in reducing salt in foods

ILSI SEAR Australasia and the Australian Institute of Food Science and Technology are pleased to invite you to a symposium on The Science of Salt: Industry innovation and best practice in reducing salt in foods.

Date                       Thursday, 2 July 2009

Venue                    The George Institute for International Health,

                                Level 7, 341 George St, Sydney (Westpac Building)

                                (Entry via Regimental Square)

Cost                       $150.00 incl. GST

Click here for further information.

 

 

Salt in the diet: Why health professionals need a shake up

This symposium, called Salt in the diet: why health professionals need a shake up is being held by the Academy of Science and sponsored by the Nutrition Society of Australia NSW Branch. It aims to raise consumer and health professionals' awareness of the health consequences of our excessive salt intake and disseminate strategies that can be implemented at a federal, state and community level to reduce dietary salt intake.

 

Speakers on the day include:

  • Professor Jennie Brand-Miller, University of Sydney
  • Professor Stewart Truswell, University of Sydney
  • Professor George Jerums, University of Melbourne
  • Dr Jennifer Keogh, CSIRO
  • Dr Russell Keast, Deakin University
  • Susan Anderson, National Heart Foundation
  • Dr Stephen Corbett, Sydney West Area Health Service
  • Professor Bruce Neal, The George Institute for International Health

 

Event details:

When: 9am to 5pm, 13 August 2009

Where: Level 7, 341 George St, Sydney

Cost: $120 ($110 for Nutrition Society of Australia members)

RSVP: peopleD pty ltd on 0417 358 894 or register@peopled.com.au

 
 
The RAAS Club: An Expanding System (AngII workshop)

Date: 9am – 5.30pm, Friday 8 October 2009

 

Venue: Monash University, Theatre M2

 

Organising Committee: Kate Denton (chair), Robert Widdop, Roger Evans, Geoff Head and Louise Burrell

 

No registration fee, only an optional dinner fee.

 

Dinner: Friday night, Cinque Lire, Monash

 

Preliminary program: 

  • Peptides, Enzymes, Receptors & Signalling
  • RAAS in Health and Disease
  • Novel Therapeutic Approaches

 

Format: invited speakers and oral snapshots from early career scientists and students

 

Invited speakers:

Professor Tony Turner

Proteolysis Research Group, University of Leeds U.K. Functional/structural studies of cell-surface peptidases involved in the metabolism of bioactive peptides –Aminopeptidases, ACE and its homologue ACE2 and the neprilysin family.

 

Professor Wally Thomas

Biochemistry & Molecular Biology Group, University of Queensland. Molecular regulation of angiotensin receptors

 

Expressions of interest to present are invited: Please contact A/Prof Kate Denton kate.denton@med.monash.edu.au

 
 
ASMR 48th National Scientific Conference

I am pleased to invite your attendance at the 48th Annual National Scientific Conference of The Australian Society for Medical Research. The theme of the meeting is "Neurogenetics on the Apple Isle" and the venue is The Grand Chancellor Hotel, Hobart, November 15-17 2009.

 
We are assembling an outstanding lineup of speakers including our Firkin Orator, Professor Jonathan Flint of the University of Oxford, UK who is investigating the genetic basis of psychiatric disorders.

 
The program covers diverse topics such as epilepsy, neuromuscular diseases, motor neurone, schizophrenia, stroke, Huntington's disease, ataxis, MS, neuropathies, brain development, mental retardation, Parkinson's disease, bipolar disorder, neurofibromatosis, muscular dystrophy and neurological diseases.

 
Abstract submission and online bookings are now open at
http://www.asmr-nsc.org.au/

 

  • Submissions for Oral selection will close Friday August 14th 2009
  • Submissions for Poster-Only selection will close Friday September 25th 2009

 

Come along and enjoy outstanding science on the enchanting Apple isle.   I look forward to seeing you there.


Regards,


Associate Professor Martin Delatycki

Conference Convenor

 

 
The 23rd Scientific Meeting of the International Society of Hypertension

The International Society of Hypertension (ISH) invites you to participate in the 23rd Scientific Meeting (ISH 2010) to be held September 26 - 30, 2010 in beautiful Vancouver, Canada. The theme of the 2010 Meeting is Global Cardiovascular Risk Reduction. Future perspectives, new research, treatment and prevention will be showcased through the Scientific Program covering four days of invited plenary talks and oral and poster presentations. Keynote speakers will include pioneers and leading investigators in the fields of cardiovascular, renal, and metabolic health. The Meeting will also include Industry and Investigator-initiated Symposia held before and after the Scientific Program at various locations in Vancouver and throughout the province of British Columbia.

 

ISH 2010 will begin accepting abstracts in June 2009. Early decisions on acceptance of abstracts will give participants a longer lead time for visa applications.

 

There is a world to discover when you visit Vancouver – Spectacular by Nature, and Beautiful British Columbia. A variety of social events that showcase the diversity and richness of Canadian culture will be planned along with optional local and regional tours that will be available both pre and post ISH 2010.

 

Visit www.vancouverhypertension2010.com for further information.

 

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Acknowledgements

HBPRCA would like to acknowledge the support of the following companies:

 

Corporate members

 

Corporate Sponsors

 

 

Meetings in 2009

ISAN09, the 6th Congress of The International Society for Autonomic Neuroscience

1 – 4 September 2009
Sydney
Click here for meeting website

World Hypertension Congress 2009 (25th anniversary)

29 October - 1 November 2009
Beijing International Conference Center, China
Click here for meeting website

 

 

 

ASMR 48th National Scientific Conference

15 - 17 November 2009
Hobart, Tasmania
Click here for meeting website

 

HBPRCA 2009 ASM

1 – 3 December 2009
Luna Park Sydney
Click here for meeting website

The 2nd International Conference on Fixed Combination in the Treatment of Hypertension, Dyslipidemia and Diabetes Mellitus

10 - 12 December 2009
Valencia, Spain
Click here for meeting website

 

 

 

Meetings in 2010

2010 Medical Applications of Synchrotron Research Meeting
15 - 18 February 2010
Melbourne Exhibition Centre
Click here for meeting website

EDDP 2010 – International Conference on Early Disease Detection and Prevention
25 – 28 February 2010

Munich, Germany

Click here for meeting website

 

 

HBPRCA Secretariat

Athina Patti at Meetings First

4/184 Main Street

LILYDALE VIC 3140

 

Phone +61 3 9739 7697

Fax +61 3 9739 7076

Email hbprca@meetingsfirst.com.au

Web www.hbprca.com.au